Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus.
Identifieur interne : 001263 ( Main/Exploration ); précédent : 001262; suivant : 001264Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus.
Auteurs : Gary Crameri ; Peter A. Durr ; Reuben Klein ; Adam Foord ; Meng Yu ; Sarah Riddell ; Jessica Haining ; Dayna Johnson ; Maged G. Hemida ; Jennifer Barr ; Malik Peiris ; Deborah Middleton ; Lin-Fa WangSource :
- Emerging infectious diseases [ 1080-6059 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (immunologie), Anticorps antiviraux (sang), Anticorps neutralisants (immunologie), Anticorps neutralisants (sang), Camélidés du Nouveau Monde (immunologie), Camélidés du Nouveau Monde (virologie), Charge virale, Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Excrétion virale, Femelle, Infections à coronavirus (immunologie), Infections à coronavirus (virologie), Modèles animaux de maladie humaine, Tests de neutralisation.
- MESH :
- immunologie : Anticorps antiviraux, Anticorps neutralisants, Camélidés du Nouveau Monde, Coronavirus du syndrome respiratoire du Moyen-Orient, Infections à coronavirus.
- sang : Anticorps antiviraux, Anticorps neutralisants.
- virologie : Camélidés du Nouveau Monde, Infections à coronavirus.
- Animaux, Charge virale, Excrétion virale, Femelle, Modèles animaux de maladie humaine, Tests de neutralisation.
English descriptors
- KwdEn :
- Animals, Antibodies, Neutralizing (blood), Antibodies, Neutralizing (immunology), Antibodies, Viral (blood), Antibodies, Viral (immunology), Camelids, New World (immunology), Camelids, New World (virology), Coronavirus Infections (immunology), Coronavirus Infections (virology), Disease Models, Animal, Female, Middle East Respiratory Syndrome Coronavirus (immunology), Neutralization Tests, Viral Load, Virus Shedding.
- MESH :
- chemical , blood : Antibodies, Neutralizing, Antibodies, Viral.
- chemical , immunology : Antibodies, Neutralizing, Antibodies, Viral.
- immunology : Camelids, New World, Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- virology : Camelids, New World, Coronavirus Infections.
- Animals, Disease Models, Animal, Female, Neutralization Tests, Viral Load, Virus Shedding.
Abstract
We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus.
DOI: 10.3201/eid2206.160007
PubMed: 27070733
Affiliations:
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Le document en format XML
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Hemida</name><name sortKey="Johnson, Dayna" sort="Johnson, Dayna" uniqKey="Johnson D" first="Dayna" last="Johnson">Dayna Johnson</name><name sortKey="Klein, Reuben" sort="Klein, Reuben" uniqKey="Klein R" first="Reuben" last="Klein">Reuben Klein</name><name sortKey="Middleton, Deborah" sort="Middleton, Deborah" uniqKey="Middleton D" first="Deborah" last="Middleton">Deborah Middleton</name><name sortKey="Peiris, Malik" sort="Peiris, Malik" uniqKey="Peiris M" first="Malik" last="Peiris">Malik Peiris</name><name sortKey="Riddell, Sarah" sort="Riddell, Sarah" uniqKey="Riddell S" first="Sarah" last="Riddell">Sarah Riddell</name><name sortKey="Wang, Lin Fa" sort="Wang, Lin Fa" uniqKey="Wang L" first="Lin-Fa" last="Wang">Lin-Fa Wang</name><name sortKey="Yu, Meng" sort="Yu, Meng" uniqKey="Yu M" first="Meng" last="Yu">Meng Yu</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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